The 2010 United States Census reported that La Mesa had a population of 57,065. The population density was 6,259.6 people per square mile. The racial makeup of La Mesa was 40,964 (71.8%) White, Hispanic or Latino of any race were 11,696 persons (20.5%), 4,399 (7.7%) African American, 431 (0.8%) Native American, 3,289 (5.8%) Asian, 318 (0.6%) Pacific Islander, 4,326 (7.6%) from other races, and 3,338 (5.8%) from two or more races.

There were 24,512 households, out of which 6,695 (27.3%) had children under the age of 18 living in them, 9,330 (38.1%) were opposite living together, 3,102 (12.7%) had a female householder with no husband present, 1,335 (5.4%) had a male householder with no wife present.  Eight thousand and four households (32.7%) were made up of individuals and 2,924 (11.9%) had someone living alone who was 65 years of age or older. The average household size was 2.30. There were 13,767 families (56.2% of all households); the average family size was 2.94.

The population was spread out with 11,164 people (19.6%) under the age of 18, 6,396 people (11.2%) aged 18 to 24, 16,792 people (29.4%) aged 25 to 44, 14,625 people (25.6%) aged 45 to 64, and 8,088 people (14.2%) who were 65 years of age or older. The median age was 37.1 years. For every 100 females there were 90.8 males. For every 100 females age 18 and over, there were 88.1 males.

There were 26,167 housing units at an average density of 2,870.3 per square mile (1,108.2/km²), of which 11,221 (45.8%) were owner-occupied, and 13,291 (54.2%) were occupied by renters. The homeowner vacancy rate was 1.4%; the rental vacancy rate was 7.2%. 26,713 people (46.8% of the population) lived in owner-occupied housing units and 29,695 people (52.0%) lived in rental housing units.

Source: 2010 Census 

Who are La Mesa's Famous Faces?

La Mesa is the hometown of these amazing people:

NBA player Bill Walton

NFL Quarterback Alex Smith

MasterChef winner Claudia Sandoval

True-crime author Cathy Scott

Baseball players Aaron Boone and Brooks Conrad 

Singer of rock band Pearl Jam, Eddie Vedder grew up in La Mesa, CA

Megadeth founder and guitarist/singer Dave Mustaine